Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 12-Aminododecanoic Acid SCHEMBL34463223 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| SCHEMBL17290449 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| SCHEMBL8107615 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| Aminocaproic Acid SCHEMBL4608459 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| Aminocaproic Acid SCHEMBL11121733 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| Potassium Ion SCHEMBL11126518 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| Aminocaproic Acid SCHEMBL9128426 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| Aminocaproic Acid SCHEMBL15401287 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| SCHEMBL11123518 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB | |
| SCHEMBL30279462 | 0.95 | LMNA (0.56) | LMNAMEN1ALDH1A1PLGTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917293-B1 | METHOD FOR IMPROVING COATING CURE FOR ARTICLE COATED IN PHOSPHATE-CONTAMINATED ELECTROCOAT COATING COMPOSITION AND ELECTROCOAT COATING COMPOSITION | BASF COATINGS GMBH (DE) | 2017-11-15 | — | — | EP | disclosed |
| US-20150267315-A1 | Method For Improving Coating Cure For Article Coated In Phosphate-Contaminated Electrocoat Coating Composition And Electrocoat Coating Composition | BASF COATINGS GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2917293-A1 | METHOD FOR IMPROVING COATING CURE FOR ARTICLE COATED IN PHOSPHATE-CONTAMINATED ELECTROCOAT COATING COMPOSITION AND ELECTROCOAT COATING COMPOSITION | BASF Coatings GmbH (DE) | 2015-09-16 | — | — | EP | disclosed |
| WO-2014074234-A1 | METHOD FOR IMPROVING COATING CURE FOR ARTICLE COATED IN PHOSPHATE-CONTAMINATED ELECTROCOAT COATING COMPOSITION AND ELECTROCOAT COATING COMPOSITION | BASF COATINGS GMBH (DE) | 2014-05-15 | — | — | WO | disclosed |
| EP-1539889-B1 | ELECTRODEPOSITION BATHS CONTAINING METAL SALTS AND METHODS RELATED THERETO | PPG IND OHIO INC (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1539889-A1 | ELECTRODEPOSITION BATHS CONTAINING METAL SALTS AND METHODS RELATED THERETO | PPG Industries Ohio, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040050704-A1 | Electrodeposition baths containing metal salts and methods related thereto | PPG INDUSTRIES OHIO, INC. | 2004-03-18 | — | — | US | disclosed |
| WO-2004000955-A1 | ELECTRODEPOSITION BATHS CONTAINING METAL SALTS AND METHODS RELATED THERETO | PPG INDUSTRIES OHIO, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| EP-0927232-B1 | ELECTRODEPOSITABLE COATING COMPOSITION CONTAINING BISMUTH AND AMINO ACID MATERIALS AND ELECTRODEPOSITION METHOD | PPG IND OHIO INC (US) | 2002-01-16 | — | — | EP | disclosed |