Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453503 | 0.99 | HMGCR (0.37) | HMGCRSMN1; SMN2HSPA5CYP2C19POLB | |
| SCHEMBL4451531 | 0.99 | HMGCR (0.37) | HMGCRSMN1; SMN2HSPA5CYP2C19POLB | |
| SCHEMBL2334334 | 0.81 | TRPV1 (0.34) | HMGCRCYP2C19MEN1GAAKMT2A | |
| SCHEMBL4445850 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP2C19POLBS1PR1S1PR3 | |
| SCHEMBL1132180 | 0.79 | TRPV1 (0.34) | HMGCRCYP2C19MEN1GAAKMT2A | |
| SCHEMBL4447604 | 0.79 | ALDH1A1 (0.34) | HMGCRSMN1; SMN2POLBTRPA1ALDH1A1 | |
| SCHEMBL9660052 | 0.79 | TRPV1 (0.34) | HMGCRCYP2C19MEN1GAAKMT2A | |
| SCHEMBL4453671 | 0.79 | ALDH1A1 (0.34) | HMGCRSMN1; SMN2POLBTRPA1ALDH1A1 | |
| SCHEMBL888650 | 0.79 | TRPV1 (0.34) | HMGCRCYP2C19MEN1GAAKMT2A | |
| SCHEMBL22100 | 0.79 | TRPV1 (0.34) | HMGCRCYP2C19MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375538-B1 | PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION | IDEMITSU KOSAN CO (JP) | 2008-01-09 | — | — | EP | disclosed |