SCHEMBL495774

SCHEMBL495774

O=C(O)CC(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518985 1.00
SCHEMBL7519154 1.00
SCHEMBL1262446 0.84 SLC22A6 (0.50)
SCHEMBL6734706 0.81 SLC22A6 (0.47)
SCHEMBL4284728 0.78
SCHEMBL7521331 0.77
SCHEMBL7520601 0.77
SCHEMBL7525449 0.77
SCHEMBL6049457 0.77
SCHEMBL7920483 0.76 SLC22A6 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113960307-B Test strip for detecting isoprothiolane and preparation method and application thereof 北京勤邦科技股份有限公司 2023-07-07 CN claimed
CN-113788814-B Hapten for detecting isoprothiolane content, preparation method and application thereof 云南省烟草质量监督检测站 2022-07-01 CN claimed
CN-113960307-A Test strip for detecting isoprothiolane and preparation method and application thereof 北京勤邦生物技术有限公司 2022-01-21 CN claimed
CN-113788814-A Hapten for detecting content of isoprothiolane, preparation method and application thereof 云南省烟草质量监督检测站 2021-12-14 CN claimed
EP-0202157-B1 N-SUBSTITUTED 2-AMINO-THIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE LABORATOIRES CHAUVIN S.A. (FR) 1989-08-23 EP claimed
US-4675448-A Chlorination process ETHYL CORPORATION (US) 1987-06-23 US claimed
JP-10251135-A None JP disclosed
EP-4632110-A1 PROCESS FOR THE HALOGENATION OF ORGANIC COMPOUNDS ESy-Labs-GmbH (DE) 2025-10-15 EP disclosed
EP-4632111-A2 PROCESS FOR THE PREPARATION OF ACETALS OF ALPHA-CHLORO- OR ALPHA-BROMO-ALDEHYDES ESy-Labs-GmbH (DE) 2025-10-15 EP disclosed
WO-2024086259-A1 METHOD FOR PREPARING CHLORINE-CONTAINING BENZAMIDE DERIVATIVES FMC CORPORATION (US) 2024-04-25 WO disclosed
WO-2023143194-A1 CCR4 SMALL MOLECULE ANTAGONIST AND USE THEREOF 瑞石生物医药有限公司 2023-08-03 WO disclosed
CN-113960307-B Test strip for detecting isoprothiolane and preparation method and application thereof 北京勤邦科技股份有限公司 2023-07-07 CN disclosed
CN-113264945-B Spiro derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-11-22 CN disclosed
WO-1998012182-A1 1-SULFONYL-3-PHENYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING OR DEFOLIATING PLANTS BASF AKTIENGESELLSCHAFT (DE) 1998-03-26 WO disclosed
WO-1997035845-A1 SUBSTITUTED 1-METHYL-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-10-02 WO disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
EP-0209435-B1 Hydroxyalkoxy-4-phenylpropyl indole derivatives, their salts, process and intermediates for their preparation, use as medicines and compositions containing them ROUSSEL UCLAF (FR) 1993-11-24 EP disclosed
EP-0209435-A1 Hydroxyalkoxy-4-phenylpropyl indole derivatives, their salts, process and intermediates for their preparation, use as medicines and compositions containing them ROUSSEL-UCLAF (FR) 1987-01-21 EP disclosed
US-4533664-A Antithrombotic N-(6-chloro-pyrazin-2-yl)-4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide derivatives, composition, and method of use DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-08-06 US disclosed
US-3960829-A Process for acylation of amino, imino and hydroxyl groups using pyrimidine derivatives NITTO BOSEKI CO., LTD. (JA) 1976-06-01 US disclosed