⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525449 | 1.00 | — | — | |
| SCHEMBL7521331 | 1.00 | — | — | |
| SCHEMBL1262446 | 0.84 | SLC22A6 (0.50) | — | |
| SCHEMBL6734706 | 0.81 | SLC22A6 (0.47) | — | |
| SCHEMBL495774 | 0.77 | — | — | |
| SCHEMBL7518985 | 0.77 | — | — | |
| SCHEMBL7519154 | 0.77 | — | — | |
| SCHEMBL10438656 | 0.74 | — | — | |
| SCHEMBL6460666 | 0.74 | — | — | |
| SCHEMBL7515281 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| EP-0869777-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997022338-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |
| EP-0364100-A2 | Process for the chlorination of sugars | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1990-04-18 | — | — | EP | disclosed |