Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009630 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL524648 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL30655986 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL1673169 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL29425228 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL702670 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL2510639 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL6384699 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL31006936 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 | |
| SCHEMBL10511364 | 0.85 | PAX8 (0.32) | ALDH1A1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962642-A | TREATING PROTEIN/PEPTIDE HAVING AMINO TERMINAL ACETYLATED AMINO ACID WITH ACID TO ACETYLATE HYDROXYL GROUP, TREATING WITH ISOTHIOCYANATE COMPOUND IN PRESENCE OF ACID TO FORM THIOCARBAMYL PROTEIN/PEPTIDE, ANALYSIS BY EDMAN DEGRADATION | SEIKO INSTRUMENTS INC. (JP) | 1999-10-05 | — | — | US | claimed |
| US-7432245-B2 | Pharmaceutical formulation comprising a peptide angiogenesis inhibitor | ABBOTT LABORATORIES INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-5962642-A | TREATING PROTEIN/PEPTIDE HAVING AMINO TERMINAL ACETYLATED AMINO ACID WITH ACID TO ACETYLATE HYDROXYL GROUP, TREATING WITH ISOTHIOCYANATE COMPOUND IN PRESENCE OF ACID TO FORM THIOCARBAMYL PROTEIN/PEPTIDE, ANALYSIS BY EDMAN DEGRADATION | SEIKO INSTRUMENTS INC. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5633232-A | ANALGESIC, ANTIHISTAMINE, SKIN DISORDERS, VISION DEFECTS,ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5420297-A | Antiinflammatory agents, ophthalmic and antiarthritic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| WO-1994020126-A1 | USE OF PEPTIDES FOR THE MANUFACTURE OF A MEDICAMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |
| EP-0590152-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022569-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | WO | disclosed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0482539-A2 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |