Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBK | Q96KB5 | 11/20 | 0.51 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 4/20 | 0.44 |
| ▸ | FEN1 | P39748 | 4/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 4/20 | 0.44 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157850 | 0.86 | PBK (0.51) | PBKGSK3BERCC1FEN1ERCC4 | |
| SCHEMBL4959665 | 0.85 | GSK3B (0.48) | PBKGSK3B | |
| SCHEMBL4958910 | 0.85 | GSK3B (0.45) | PBKGSK3B | |
| SCHEMBL4157191 | 0.84 | GSK3B (0.51) | PBKGSK3BERCC1FEN1ERCC4 | |
| SCHEMBL4161593 | 0.83 | PBK (0.48) | PBKGSK3B | |
| SCHEMBL4166755 | 0.83 | GSK3B (0.56) | PBKGSK3BERCC1FEN1ERCC4 | |
| SCHEMBL4961799 | 0.83 | GSK3B (0.42) | GSK3B | |
| SCHEMBL4958340 | 0.82 | GSK3B (0.55) | PBKGSK3B | |
| SCHEMBL4145737 | 0.81 | PBK (0.51) | PBKGSK3B | |
| SCHEMBL8240596 | 0.81 | PBK (0.76) | PBKGSK3BERCC1FEN1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984370-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Crystalgenomics, Inc. (KR) | 2008-10-29 | — | — | EP | claimed |
| WO-2007083978-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-07-26 | — | — | WO | claimed |