Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958340 | 0.89 | GSK3B (0.55) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4958910 | 0.88 | GSK3B (0.45) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4161592 | 0.86 | GSK3B (0.57) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4961799 | 0.86 | GSK3B (0.42) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4957874 | 0.85 | PBK (0.51) | GSK3BPBK | |
| SCHEMBL4152714 | 0.83 | GSK3B (0.59) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4958224 | 0.82 | GSK3B (0.53) | GSK3BPBKHIF1AEGLN1 | |
| SCHEMBL4157364 | 0.82 | GSK3B (0.48) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4958297 | 0.81 | PBK (0.35) | GSK3BMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4161210 | 0.81 | GSK3B (0.53) | GSK3BMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984370-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Crystalgenomics, Inc. (KR) | 2008-10-29 | — | — | EP | claimed |
| WO-2007083978-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-07-26 | — | — | WO | claimed |