Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957059 | 0.86 | CYP1A2 (0.61) | POLBALDH1A1KMT2AHPGDCYP1A2 | |
| SCHEMBL23295963 | 0.80 | ALDH1A1 (0.52) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL28229016 | 0.78 | ALDH1A1 (0.44) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL31538653 | 0.75 | ALDH1A1 (0.48) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL7028014 | 0.75 | CYP1A2 (0.47) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL14263853 | 0.74 | HDAC3 (0.73) | POLBALDH1A1KMT2AHPGDCYP1A2 | |
| SCHEMBL6317855 | 0.74 | ALDH1A1 (0.56) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7035051 | 0.74 | CYP1A2 (0.46) | POLBALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4565884 | 0.73 | HDAC3 (0.57) | POLBALDH1A1KMT2AHPGDCYP1A2 | |
| SCHEMBL31531432 | 0.72 | KMT2A (0.59) | POLBALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094909-A2 | QUINAZOLINONE AND FUSED PYRIMIDINONE COMPOUNDS AND THEIR USE IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-08-07 | — | — | WO | disclosed |