Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28732841 | 0.97 | CES1 (0.48) | CES1CES2AKR1B1HIF1AKMT2A | |
| SCHEMBL24098561 | 0.81 | SLC6A4 (0.53) | KMT2AALDH1A1LMNASMN1; SMN2IDO1 | |
| SCHEMBL9828347 | 0.78 | CES1 (0.50) | CES1CES2AKR1B1HIF1AKMT2A | |
| SCHEMBL12095508 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1KMT2AALDH1A1 | |
| SCHEMBL8993215 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1HIF1AKMT2A | |
| SCHEMBL822099 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1KMT2AALDH1A1 | |
| SCHEMBL2241627 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1KMT2AALDH1A1 | |
| SCHEMBL5184996 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1HIF1AKMT2A | |
| SCHEMBL28085046 | 0.78 | CES1 (0.55) | CES1CES2AKR1B1HIF1AKMT2A | |
| SCHEMBL23891925 | 0.77 | ABAT (0.50) | LOXL2NOS2HDAC6NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153890-B1 | DERIVATIVES OF 3-PHENYL-2-PROPENAMINE, THEIR PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-01-04 | — | — | EP | claimed |
| US-4755599-A | 3-phenyl-2-propeneamine derivatives, their preparation and composition containing them | RHONE-POULENC SANTE (FR) | 1988-07-05 | — | — | US | claimed |
| US-4686309-A | ANTIDEPRESSANTS | RHONE-POULENC SANTE (FR) | 1987-08-11 | — | — | US | claimed |
| CN-116156919-A | Light-emitting device, preparation method thereof and display device | TCL科技集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-3345982-A1 | DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG Chem, Ltd. (KR) | 2018-07-11 | — | — | EP | disclosed |
| WO-2018048806-A1 | CXCR4 ANTAGONISTS AND METHODS OF USE | Mainline Biosciences (US) | 2018-03-15 | — | — | WO | disclosed |
| CN-104520399-B | Adhesive composite | 日本瑞翁株式会社 | 2017-11-10 | — | — | CN | disclosed |
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-103946301-B | Acrylonitrile rubber composite and rubber cross thing | ZEON CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-104520399-A | Adhesive agent composition | ZEON CORP | 2015-04-15 | — | — | CN | disclosed |
| US-20150050212-A1 | CHOLECYSTOKININ B RECEPTOR TARGETING FOR IMAGING AND THERAPY | PURDUE RESEARCH FOUNDATION | 2015-02-19 | — | — | US | disclosed |
| WO-1999045016-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| WO-1998039342-A1 | NOVEL INDOLE AND AZAINDOLE INHIBITORS OF FRUCTOSE-1,6-BISPHOSPHATASE | METABASIS THERAPEUTICS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
| CN-1050545-A | Inhibitors of post-infective viral proteases | HOECHST AG (DE) | 1991-04-10 | — | — | CN | disclosed |
| EP-0153890-B1 | DERIVATIVES OF 3-PHENYL-2-PROPENAMINE, THEIR PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-01-04 | — | — | EP | disclosed |
| US-4755599-A | 3-phenyl-2-propeneamine derivatives, their preparation and composition containing them | RHONE-POULENC SANTE (FR) | 1988-07-05 | — | — | US | disclosed |
| US-4755599-A | 3-phenyl-2-propeneamine derivatives, their preparation and composition containing them | RHONE-POULENC SANTE (FR) | 1988-07-05 | — | — | US | disclosed |
| US-4686309-A | ANTIDEPRESSANTS | RHONE-POULENC SANTE (FR) | 1987-08-11 | — | — | US | disclosed |
| US-4686309-A | ANTIDEPRESSANTS | RHONE-POULENC SANTE (FR) | 1987-08-11 | — | — | US | disclosed |
| EP-0153890-A2 | Derivatives of 3-phenyl-2-propenamine, their preparation and medicines containing them | RHONE-POULENC SANTE (FR) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050212-A1 | CHOLECYSTOKININ B RECEPTOR TARGETING FOR IMAGING AND THERAPY | CCKBR, CCKAR, GRPR | CES1 1273/4885CES2 1550/4885AKR1B1 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.