Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 14/20 | 0.65 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571029 | 0.90 | SSTR5 (0.78) | SSTR5CXCR3RORCDHODHEHMT2 | |
| SCHEMBL4955154 | 0.86 | SSTR5 (0.58) | SSTR5RORCDHODH | |
| SCHEMBL4958519 | 0.83 | SSTR5 (0.54) | SSTR5RORCDHODHEHMT2 | |
| SCHEMBL4955178 | 0.82 | SSTR5 (0.81) | SSTR5 | |
| SCHEMBL4952476 | 0.81 | SSTR5 (0.72) | SSTR5 | |
| SCHEMBL4954442 | 0.81 | SSTR5 (0.57) | SSTR5CXCR3 | |
| SCHEMBL4955761 | 0.81 | SSTR5 (0.69) | SSTR5 | |
| SCHEMBL3571056 | 0.79 | SSTR5 (1.00) | SSTR5CXCR3EZH2 | |
| SCHEMBL4958309 | 0.78 | SSTR5 (0.67) | SSTR5 | |
| SCHEMBL3572094 | 0.75 | SSTR5 (0.70) | SSTR5RORCDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858901-B1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | EP | disclosed |