Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 11/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955151 | 0.86 | SSTR5 (0.49) | SSTR5RORCDHODHPOLBLTA4H | |
| SCHEMBL4958525 | 0.83 | SSTR5 (0.65) | SSTR5RORCDHODHEHMT2 | |
| SCHEMBL3571029 | 0.83 | SSTR5 (0.78) | SSTR5RORCDHODHEHMT2 | |
| SCHEMBL4955177 | 0.81 | SSTR5 (0.70) | SSTR5LTA4H | |
| SCHEMBL4952469 | 0.80 | SSTR5 (0.61) | SSTR5EHMT2LTA4H | |
| SCHEMBL4954437 | 0.80 | SSTR5 (0.48) | SSTR5RORCDHODHPOLBLTA4H | |
| SCHEMBL4955756 | 0.80 | SSTR5 (0.59) | SSTR5LTA4H | |
| SCHEMBL4958304 | 0.77 | SSTR5 (0.57) | SSTR5LTA4H | |
| SCHEMBL4958527 | 0.72 | SSTR5 (0.43) | SSTR5HTR1A | |
| SCHEMBL3571056 | 0.71 | SSTR5 (1.00) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858901-B1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | EP | disclosed |