Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355722 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDALOX15ELANEMEN1 | |
| SCHEMBL18355727 | 0.87 | ALDH1A1 (0.51) | ALDH1A1ALOX15ELANECYP1A2SMN1; SMN2 | |
| SCHEMBL18356070 | 0.85 | ELANE (0.50) | ALDH1A1HPGDALOX15MAPTELANE | |
| SCHEMBL1078509 | 0.84 | TP53 (0.58) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL3002505 | 0.79 | MAPT (0.57) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL3605776 | 0.78 | MAPT (0.48) | ALDH1A1MAPTGAASMN1; SMN2GRM5 | |
| SCHEMBL15005212 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL30007326 | 0.77 | NOTUM (0.71) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL27172293 | 0.77 | NOTUM (0.71) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL718714 | 0.75 | NPC1 (0.56) | ALDH1A1HPGDALOX15HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| EP-1874734-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2008-01-09 | — | — | EP | disclosed |
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2006-08-31 | — | — | US | disclosed |
| WO-2006087355-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | CNR1, CNR2, HRH4 | ALDH1A1 1715/4885HPGD 788/4885ALOX15 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.