Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960845 | 0.88 | MEN1 (0.32) | IDO1TDO2NPSR1CYP2D6MEN1 | |
| SCHEMBL4961262 | 0.82 | EDNRB (0.37) | IDO1TDO2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL4961609 | 0.82 | AOC3 (0.35) | ALDH1A1MAPTNPSR1SLC6A2SLC6A4 | |
| SCHEMBL532851 | 0.79 | LMNA (0.39) | ALDH1A1CYP3A4MEN1CYP1A2POLB | |
| SCHEMBL3623440 | 0.77 | LMNA (0.38) | CYP3A4KCNH2MEN1CYP1A2POLB | |
| SCHEMBL7747171 | 0.77 | LMNA (0.38) | ALDH1A1CYP3A4MEN1CYP1A2POLB | |
| Ammonia Solution, Strong SCHEMBL8366918 | 0.77 | LMNA (0.38) | ALDH1A1CYP3A4MEN1CYP1A2POLB | |
| SCHEMBL7667921 | 0.77 | CYP1A2 (0.32) | IDO1TDO2CYP2D6SLC6A2SLC6A4 | |
| Trimethylammonium SCHEMBL9451107 | 0.75 | LMNA (0.36) | ALDH1A1HTTCYP3A4CYP2D6SLC6A4 | |
| Tetramethylammonium Ion SCHEMBL2428729 | 0.75 | LMNA (0.36) | CYP3A4CYP2D6MEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032576-B1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON ALPHA-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| EP-1032576-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | Ciba SC Holding AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| WO-1998038195-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMMONIUM KETONES, IMINIUM KETONES OR AMIDINIUM KETONES AND ARYL BORATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-09-03 | — | — | WO | disclosed |