Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.65 |
| ▸ | DPP4 | P27487 | 8/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943473 | 0.96 | PREP (0.69) | PREPDPP4DPP7DPP8DPP9 | |
| SCHEMBL1437419 | 0.96 | PREP (0.69) | PREPDPP4DPP7DPP8DPP9 | |
| SCHEMBL1437422 | 0.96 | PREP (0.69) | PREPDPP4DPP7DPP8DPP9 | |
| SCHEMBL9701705 | 0.87 | PREP (0.65) | PREPDPP4 | |
| SCHEMBL9702352 | 0.87 | PREP (0.65) | PREPDPP4 | |
| SCHEMBL7286320 | 0.84 | PREP (0.55) | PREP | |
| SCHEMBL7286213 | 0.84 | PREP (0.55) | PREP | |
| SCHEMBL13424971 | 0.83 | SMN1; SMN2 (0.54) | PREP | |
| SCHEMBL28528115 | 0.82 | PREP (0.48) | PREPFKBP1A | |
| SCHEMBL28528114 | 0.82 | PREP (0.48) | PREPFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039882-A1 | A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST | SANOFI-AVENTIS U.S. LLC (US) | 2008-04-03 | — | — | WO | disclosed |