Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702352 | 1.00 | PREP (0.65) | PREPDPP4CTRB1 | |
| SCHEMBL1437422 | 0.91 | PREP (0.69) | PREPDPP4 | |
| SCHEMBL1437419 | 0.91 | PREP (0.69) | PREPDPP4 | |
| SCHEMBL943473 | 0.91 | PREP (0.69) | PREPDPP4 | |
| SCHEMBL9701702 | 0.87 | PREP (0.67) | PREPDPP4CTRB1 | |
| SCHEMBL4959347 | 0.87 | PREP (0.65) | PREPDPP4 | |
| SCHEMBL17459415 | 0.84 | PREP (0.71) | PREPCTRB1 | |
| SCHEMBL20678314 | 0.84 | PREP (0.71) | PREPCTRB1 | |
| SCHEMBL17459445 | 0.84 | PREP (0.71) | PREPCTRB1 | |
| SCHEMBL18093534 | 0.84 | PREP (0.71) | PREPCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | claimed |
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |