Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917714 | 0.96 | CYP2C9 (0.35) | CYP2C9POLBKMT2AMAPTTHRB | |
| SCHEMBL2924529 | 0.96 | CYP2C9 (0.34) | CYP2C9POLBKMT2AMAPTTHRB | |
| SCHEMBL2915854 | 0.96 | CYP2C9 (0.34) | CYP2C9POLBKMT2AMAPTTHRB | |
| SCHEMBL2923691 | 0.95 | FKBP1A (0.35) | CYP2C9POLBKMT2AMAPTLMNA | |
| SCHEMBL2916770 | 0.95 | FKBP1A (0.35) | CYP2C9POLBKMT2AMAPTLMNA | |
| SCHEMBL2923505 | 0.95 | CYP2C9 (0.34) | CYP2C9POLBKMT2AMAPTTHRB | |
| SCHEMBL2922511 | 0.94 | KMT2A (0.34) | CYP2C9POLBKMT2AMAPTLMNA | |
| SCHEMBL1517910 | 0.93 | CYP2C9 (0.32) | CYP2C9POLBKMT2ARORC | |
| SCHEMBL1517854 | 0.93 | CYP2C9 (0.32) | CYP2C9POLBKMT2ARORC | |
| SCHEMBL1517856 | 0.93 | CYP2C9 (0.32) | CYP2C9POLBKMT2ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1897879-A2 | 2,4,5 substituted piperidines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-03-12 | — | — | EP | disclosed |