Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040946 | 0.96 | REN (0.31) | REN | |
| SCHEMBL1517998 | 0.95 | REN (0.31) | REN | |
| SCHEMBL1517810 | 0.94 | — | — | |
| SCHEMBL1517811 | 0.94 | — | — | |
| SCHEMBL2918851 | 0.94 | REN (0.32) | REN | |
| SCHEMBL2389135 | 0.92 | — | — | |
| SCHEMBL2389133 | 0.92 | — | — | |
| SCHEMBL4961314 | 0.90 | REN (0.32) | REN | |
| SCHEMBL2918021 | 0.86 | REN (0.31) | REN | |
| SCHEMBL1518000 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1897879-A2 | 2,4,5 substituted piperidines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-03-12 | — | — | EP | disclosed |