Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.75 |
| ▸ | ECE1 | P42892 | 6/20 | 0.74 |
| ▸ | ACE | P12821 | 2/20 | 0.69 |
| ▸ | IL1RN | P18510 | 7/20 | 0.68 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.68 |
| ▸ | ANPEP | P15144 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959992 | 1.00 | ERAP2 (0.75) | ERAP2ECE1ACEIL1RNERAP1 | |
| SCHEMBL30051783 | 0.96 | ECE1 (0.70) | ERAP2ECE1ACEIL1RNERAP1 | |
| SCHEMBL9822631 | 0.96 | ECE1 (0.70) | ERAP2ECE1ACEIL1RNERAP1 | |
| SCHEMBL29380143 | 0.95 | ERAP2 (0.69) | ERAP2ECE1ACEIL1RNERAP1 | |
| SCHEMBL30051087 | 0.93 | ACE (0.75) | ERAP2ECE1ACE | |
| SCHEMBL2488765 | 0.93 | ACE (0.78) | ECE1ACE | |
| SCHEMBL9235805 | 0.93 | ACE (0.78) | ECE1ACE | |
| SCHEMBL1228369 | 0.93 | ACE (0.78) | ECE1ACE | |
| SCHEMBL9235801 | 0.93 | ACE (0.78) | ECE1ACE | |
| SCHEMBL29400177 | 0.93 | ACE (0.78) | ECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402561-B2 | Compositions and methods for inhibiting abnormal cell growth | CLAWNOR, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| WO-2005087251-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ABNORMAL CELL GROWTH | CLAWNOR, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050209150-A1 | Compositions and methods for inhibiting abnormal cell growth | CLAWNOR, INC. | 2005-09-22 | — | — | US | disclosed |