Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.78 |
| ▸ | ECE1 | P42892 | 12/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235805 | 1.00 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL29400177 | 1.00 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL1228369 | 1.00 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL2488765 | 1.00 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL30051087 | 0.98 | ACE (0.75) | ACEECE1ALOX15 | |
| SCHEMBL30051627 | 0.95 | ACE (0.72) | ACEECE1ALOX15 | |
| SCHEMBL3497589 | 0.95 | ACE (0.72) | ACEECE1ALOX15 | |
| SCHEMBL4959992 | 0.93 | ERAP2 (0.75) | ACEECE1 | |
| SCHEMBL4959976 | 0.93 | ERAP2 (0.75) | ACEECE1 | |
| SCHEMBL30052301 | 0.93 | ACE (0.69) | ACEECE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728145-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | Ciba-Geigy Japan Limited (JP) | 1996-08-28 | — | — | EP | disclosed |