Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL10002813 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL318366 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL15769141 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL514605 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL57827 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL301207 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL637278 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL94686 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL6720430 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| Hexane SCHEMBL4897173 | 1.00 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100516066-C | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | CN | disclosed |
| US-7423048-B2 | Compounds for treating fundic disaccomodation | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-09-09 | — | — | US | disclosed |
| CN-1288157-C | Dioxinopyridine compounds for the treatment of impaired fundic relaxation, process for their preparation and their use | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-06 | — | — | CN | disclosed |
| US-20060142318-A1 | Compounds for treating fundic disaccomodation | VAN EMELEN KRISTOF | 2006-06-29 | — | — | US | disclosed |
| CN-1781921-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2006-06-07 | — | — | CN | disclosed |
| CN-1437602-A | Compounds for treating impaired fundic relaxation | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-20 | — | — | CN | disclosed |
| EP-1296987-A1 | COMPOUNDS FOR TREATING IMPAIRED FUNDIC RELAXATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001098306-A1 | COMPOUNDS FOR TREATING IMPAIRED FUNDIC RELAXATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142318-A1 | Compounds for treating fundic disaccomodation | ALK, ADORA1, CHRM2 | ALDH1A1 130/4885LMNA 3093/4885HSD17B10 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.