Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | FPR2 | P25090 | 5/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028552 | 0.81 | ELANE (0.49) | ELANEARSCN9AFPR2SMN1; SMN2 | |
| SCHEMBL10353108 | 0.81 | ELANE (0.49) | ELANEARSCN9AFPR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29659031 | 0.80 | ELANE (0.48) | ELANEARSCN9AFPR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18920859 | 0.76 | DPP4 (0.34) | PIM1SLC6A7RIPK1 | |
| SCHEMBL2638702 | 0.75 | ELANE (0.49) | ELANEARSCN9AFPR2MAT2A | |
| SCHEMBL2638698 | 0.75 | ELANE (0.49) | ELANEARSCN9AFPR2MAT2A | |
| SCHEMBL31173895 | 0.74 | PIM1 (0.56) | ELANEARVNN1SMN1; SMN2PIM1 | |
| SCHEMBL28570406 | 0.74 | PIM1 (0.56) | ELANEARVNN1SMN1; SMN2PIM1 | |
| SCHEMBL15664903 | 0.74 | PIM1 (0.56) | ELANEARVNN1SMN1; SMN2PIM1 | |
| SCHEMBL28510719 | 0.74 | AR (0.50) | ELANEARSCN9AVNN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896452-A2 | N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis Pharma AG. (CH) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006127576-A2 | N - FORMYL HYDROXYLAMINE COMPOUNDS AS PDF INHIBITORS | NOVARTIS AG (CH) | 2006-11-30 | — | — | WO | disclosed |