Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAT2A | P31153 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353108 | 1.00 | ELANE (0.49) | ELANEARALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29659031 | 0.99 | ELANE (0.48) | ELANEARALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21853236 | 0.87 | SMN1; SMN2 (0.56) | ALDH1A1KDM4ESMN1; SMN2HSD17B10MMP1 | |
| SCHEMBL21853250 | 0.87 | SMN1; SMN2 (0.56) | ALDH1A1KDM4ESMN1; SMN2HSD17B10MMP1 | |
| SCHEMBL16238706 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ESMN1; SMN2HSD17B10MMP1 | |
| SCHEMBL29658954 | 0.82 | MMP1 (0.46) | ALDH1A1KDM4ESMN1; SMN2HSD17B10MMP1 | |
| SCHEMBL15129357 | 0.81 | ELANE (0.47) | ELANEARKDM4ESMN1; SMN2MAT2A | |
| SCHEMBL28059132 | 0.81 | MMP1 (0.47) | ALDH1A1KDM4EHSD17B10MMP1HTT | |
| SCHEMBL4960412 | 0.81 | ELANE (0.45) | ELANEARSMN1; SMN2MAT2ASCN9A | |
| SCHEMBL29200835 | 0.80 | PORCN (0.53) | ALDH1A1KDM4EHSD17B10MMP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451067-A | DNA polymerase theta inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |