Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609817 | 1.00 | HSD11B1 (0.57) | HSD11B1ALDH1A1LMNATSHRHTT | |
| SCHEMBL609816 | 1.00 | HSD11B1 (0.57) | HSD11B1ALDH1A1LMNATSHRHTT | |
| SCHEMBL610204 | 0.89 | TSHR (0.50) | HSD11B1ALDH1A1LMNATSHRHTT | |
| SCHEMBL610203 | 0.89 | TSHR (0.50) | HSD11B1ALDH1A1LMNATSHRHTT | |
| SCHEMBL20456972 | 0.81 | HSD11B1 (0.65) | HSD11B1ALDH1A1HTTTP53MAPT | |
| SCHEMBL4963055 | 0.79 | HSD11B1 (0.85) | HSD11B1RAB9A | |
| SCHEMBL609710 | 0.79 | HSD11B1 (0.85) | HSD11B1RAB9A | |
| SCHEMBL609711 | 0.79 | HSD11B1 (0.85) | HSD11B1RAB9A | |
| SCHEMBL610185 | 0.79 | HSD11B1 (0.85) | HSD11B1RAB9A | |
| SCHEMBL5243753 | 0.78 | HSD11B1 (0.72) | HSD11B1TSHRTP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |