Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381301 | 0.80 | POLB (0.44) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL6071544 | 0.70 | TSHR (0.46) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL1157213 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL21708676 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KDM4ETRPA1NPC1RAB9A | |
| SCHEMBL1759611 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL6071827 | 0.67 | CYP2A13 (0.54) | ALDH1A1KMT2AL3MBTL1MEN1CYP2C19 | |
| SCHEMBL6161477 | 0.66 | ALDH1A1 (0.60) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL4897337 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL16054766 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL9355230 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |