Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960825 | 0.92 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6090966 | 0.88 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL6090971 | 0.88 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL6092696 | 0.85 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL4961829 | 0.85 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL3841427 | 0.82 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL3841275 | 0.82 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL3841425 | 0.82 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL3838928 | 0.80 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL13616934 | 0.80 | CRHR1 (0.56) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871763-A1 | SUBSTITUTED ARYL 1.4-PYRAZlNE DERIVATIVES | Pfizer Products Inc. (US) | 2008-01-02 | — | — | EP | claimed |
| WO-2006114666-A1 | SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2006-11-02 | — | — | WO | claimed |
| EP-1871763-A1 | SUBSTITUTED ARYL 1.4-PYRAZlNE DERIVATIVES | Pfizer Products Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006114666-A1 | SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2006-11-02 | — | — | WO | disclosed |