Tetrahydrofuran

Tetrahydrofuran

SCHEMBL4960876

C1CCOC1.C1CO1.OCCO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
TTR P02766 1/20 0.43
KDM4E B2RXH2 1/20 0.42
TSHR P16473 2/20 0.36
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL11406828 1.00 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Tetrahydrofuran SCHEMBL29404 0.96
Tetrahydrofuran SCHEMBL28311130 0.96 ALDH1A1 (0.61) ALDH1A1TTRKDM4ETSHRPDK1
Tetrahydrofuran SCHEMBL10351710 0.96 ALDH1A1 (0.61) ALDH1A1TTRKDM4ETSHRPDK1
Ethylene Glycol SCHEMBL166383 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Tetrahydrofuran SCHEMBL11819032 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Ethylene Glycol SCHEMBL169649 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Tetrahydrofuran SCHEMBL18762867 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Ethylene Glycol SCHEMBL9421796 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1
Ethylene Glycol SCHEMBL2879076 0.93 ALDH1A1 (0.57) ALDH1A1TTRKDM4ETSHRPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171169-A1 Oxygen Scavenging Compositions and Method of Preparation INVISTA NORTH AMERICA S.A.R.L. (US) 2008-07-17 US disclosed
WO-2006113175-A2 OXYGEN SCAVENGING COMPOSITIONS AND METHOD OF PREPARATION INVISTA TECHNOLOGIES, S.à r.l. (CH) 2006-10-26 WO disclosed