Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217507 | 0.86 | GRM2 (0.42) | GRM2GRM3ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL10795384 | 0.81 | ALDH1A1 (0.34) | ALDH1A1DPP4 | |
| SCHEMBL10795214 | 0.81 | ALDH1A1 (0.34) | ALDH1A1DPP4 | |
| SCHEMBL10793303 | 0.80 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL10792858 | 0.79 | ALDH1A1 (0.32) | ALDH1A1DPP4 | |
| SCHEMBL10796416 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7205002 | 0.78 | FNTA (0.38) | MMP1MMP9METAP2FFAR1MMP2 | |
| SCHEMBL10798839 | 0.76 | — | — | |
| SCHEMBL10791407 | 0.75 | — | — | |
| SCHEMBL10791499 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |