SCHEMBL49610

SCHEMBL49610

COc1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.59
TDP1 Q9NUW8 3/20 0.57
CYP3A4 P08684 1/20 0.57
LTA4H P09960 2/20 0.56
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
TRPA1 O75762 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
ACHE P22303 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 1/20 0.43
PKM P14618 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25308490 1.00 CA4 (0.59) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL54543 1.00 CA4 (0.59) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL11313912 0.92 ACHE (0.60) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL15658842 0.90 CA1 (0.65) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL50047 0.90 CA1 (0.65) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL11309365 0.90 CA4 (0.48) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL10348223 0.88 CA4 (0.46) CA4TDP1CYP3A4LTA4HCA1
Iodide SCHEMBL29883618 0.87 CA1 (0.61) CA4TDP1CYP3A4LTA4HCA1
Bromide SCHEMBL28409206 0.87 CA1 (0.61) CA4TDP1CYP3A4LTA4HCA1
SCHEMBL5713323 0.87 CA1 (0.61) CA4TDP1CYP3A4LTA4HCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415819-B2 Cu- and Ni-catalyzed decarboxylative borylation reactions THE SCRIPPS RESEARCH INSTITUTE (US) 2025-09-16 US disclosed
CN-114341215-B Curable composition 株式会社日本触媒 2024-12-27 CN disclosed
US-20240352203-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE ADEKA CORPORATION (JP) 2024-10-24 US disclosed
EP-4375750-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE ADEKA CORPORATION (JP) 2024-05-29 EP disclosed
CN-117616337-A Film forming material for semiconductor, member forming material for semiconductor, process member forming material for semiconductor, underlayer film forming material, underlayer film, and semiconductor device 株式会社艾迪科 2024-02-27 CN disclosed
CN-117362339-A Preparation and application of organic phosphine oxide compound 浙江扬帆新材料股份有限公司 2024-01-09 CN disclosed
WO-2023182514-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE クラレノリタケデンタル株式会社 2023-09-28 WO disclosed
CN-113698431-B Synthesis method of phosphine (III) compound 海南大学 2023-07-25 CN disclosed
CN-115055207-B Method for preparing aryl phosphine by reducing aryl phosphine oxide 清华大学 2023-07-21 CN disclosed
WO-2023120611-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
EP-0224158-A2 Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed
US-4604386-A CONTROL OF GRAMPOSITIVE BACTERIA ELI LILLY AND COMPANY (US) 1986-08-05 US disclosed
EP-0168222-A2 3-(Alkynylalkyloxy) Cephalosporins ELI LILLY AND COMPANY (US) 1986-01-15 EP disclosed
EP-0160824-A1 Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-13 EP disclosed
US-4335240-A Process for cyclization ELI LILLY AND COMPANY (US) 1982-06-15 US disclosed
US-4293493-A Azetidinone alcohol disulfides and process for cyclization ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4257973-A USING ORGANOPHOSPHORUS-PALLADIUM HALIDE COORDINATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-24 US disclosed
US-4050939-A DISPERSION IN POLYMER MATRIX XEROX CORPORATION (US) 1977-09-27 US disclosed
US-4050937-A Imagewise exposing and heating a microimaging film containing an organo diselenide, a tertiary phosphine or phosphite and an organic peroxide XEROX CORPORATION (US) 1977-09-27 US disclosed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415819-B2 Cu- and Ni-catalyzed decarboxylative borylation reactions PCSK9, PCSK7, PCSK6 CA4 453/4885TDP1 4230/4885CYP3A4 1080/4885
US-20240352203-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE FBXL19, SRSF9, CNOT9 CA4 3423/4885TDP1 3567/4885CYP3A4 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.