Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860430 | 0.87 | MEN1 (0.48) | MEN1KMT2ARAB9AKDM4ENPSR1 | |
| SCHEMBL8784014 | 0.82 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL8784018 | 0.82 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL8784009 | 0.82 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL5810773 | 0.82 | CYSLTR1 (0.44) | MEN1KMT2ARAB9AKDM4ENPSR1 | |
| SCHEMBL8334320 | 0.81 | MEN1 (0.51) | MEN1KMT2ARAB9AKDM4ENPSR1 | |
| SCHEMBL4808042 | 0.79 | MEN1 (0.51) | MEN1KMT2ARAB9AKDM4ENPSR1 | |
| SCHEMBL29517086 | 0.77 | MEN1 (0.48) | MEN1KMT2ARAB9AKDM4ENPSR1 | |
| SCHEMBL6750524 | 0.77 | KDM4E (0.67) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL5810763 | 0.76 | MEN1 (0.46) | MEN1KMT2ARAB9AKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |