Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020024 | 0.83 | MEN1 (0.45) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL11400887 | 0.83 | NPC1 (0.66) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL29517086 | 0.82 | MEN1 (0.48) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL4961173 | 0.81 | MEN1 (0.53) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL7249222 | 0.80 | PTGER1 (0.59) | MEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL7249226 | 0.80 | PTGER1 (0.59) | MEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL3748357 | 0.79 | CCR1 (0.48) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL6969863 | 0.79 | CYSLTR2 (0.48) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL6969865 | 0.79 | CYSLTR2 (0.48) | MEN1KMT2ARAB9ANPC1NFKB1 | |
| SCHEMBL6750524 | 0.78 | KDM4E (0.67) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885987-A | ANTIHISTAMINE AGENT FOR TREATING ASTHMA, ANTILEUKOTRIENE AGENT, ANTIALLERGENS | KOWA CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5756518-A | EXHIBITS ANTILEUKOTRIENIC ACTION AND ANTIHISTAMINIC ACTION; IS USEFUL IN TREATMENT OF ASTHMA | KOWA CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |