SCHEMBL4961883

SCHEMBL4961883

CO[C@@H]1C[C@H](C(=O)Nc2ccc(-n3ccccc3=O)cc2F)N(C(=O)OC(C)(C)C)C1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4496265 0.89 F10 (0.56) F10
SCHEMBL13780947 0.86 F10 (0.61) F10
SCHEMBL15494713 0.85 F10 (0.70) F10
Eribaxaban SCHEMBL16436969 0.83 F10 (1.00) F10
Eribaxaban SCHEMBL76436 0.83 F10 (1.00) F10
Eribaxaban SCHEMBL17294640 0.83 F10 (1.00) F10
SCHEMBL3828763 0.82 F10 (0.49) F10
SCHEMBL13674870 0.82 F10 (0.62) F10
SCHEMBL4492695 0.82 F10 (0.49) F10
SCHEMBL3828777 0.82 F10 (0.48) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080194643-A1 Factor Xa Inhibitor Crystalline Forms PFZER INC 2008-08-14 — — US disclosed
EP-1891044-A1 CRYSTALLINE FORMS OF A KNOWN PYRROLIDINE FACTOR XA INHIBITOR Warner-Lambert Company LLC (US) 2008-02-27 — — EP disclosed
WO-2006100565-A1 CRYSTALLINE FORMS OF A KNOWN PYRROLIDINE FACTOR XA INHIBITOR WARNER-LAMBERT COMPANY LLC (US) 2006-09-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194643-A1 Factor Xa Inhibitor Crystalline Forms F2, F12, F2R F10 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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