Eribaxaban

Eribaxaban

SCHEMBL76436

CO[C@@H]1C[C@H](C(=O)Nc2ccc(-n3ccccc3=O)cc2F)N(C(=O)Nc2ccc(Cl)cc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eribaxaban SCHEMBL17294640 1.00 F10 (1.00) F10
Eribaxaban SCHEMBL16436969 1.00 F10 (1.00) F10
SCHEMBL3832117 0.91 F10 (0.84) F10
SCHEMBL3834852 0.91 F10 (0.84) F10
SCHEMBL3835382 0.91 F10 (0.84) F10
SCHEMBL8273153 0.91 F10 (0.84) F10
SCHEMBL3832111 0.90 F10 (0.82) F10
SCHEMBL3835174 0.90 F10 (0.82) F10
SCHEMBL3828719 0.90 F10 (0.81) F10
SCHEMBL3833371 0.90 F10 (0.81) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605371-B2 Combination therapy for cancer THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-21 US claimed
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT EPIZON PHARMA INC (US) 2026-03-26 US claimed
US-12521258-B2 Anticoagulant compounds and methods and devices for their use ELIXIR MEDICAL CORPORATION (US) 2026-01-13 US claimed
US-12514871-B2 Pegylated menaquinol compositions and methods of treatment Epizon Pharma, Inc. (US) 2026-01-06 US claimed
WO-2025132678-A1 QUALITATIVE TEST FOR DIRECT ORAL ANTICOAGULANTS (DOACS) F. HOFFMANN-LA ROCHE AG (CH) 2025-06-26 WO claimed
US-20250186563-A1 UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME ALEXION PHARMA INC (US) 2025-06-12 US claimed
CN-120060160-A Escherichia coli phage and application thereof 杭州诺安百汇医药科技有限公司 2025-05-30 CN claimed
EP-3604510-B1 ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME ALEXION PHARMA INC (US) 2025-03-26 EP claimed
US-20250092380-A1 ANTIDOTES TO FACTOR XA INHIBITORS ALEXION PHARMA INC (US) 2025-03-20 US claimed
EP-4493183-A2 TRANSDERMAL DELIVERY SYSTEMS FOR CERTAIN FACTOR XA INHIBITORS AND RELATED METHODS FOR THEIR PREPARATION AND USE Arx, LLC (US) 2025-01-22 EP claimed
WO-2022031758-A1 ANTICOAGULANT COMPOUNDS AND METHODS AND DEVICES FOR THEIR PULMONARY USE ELIXIR MEDICAL CORPORATION (US) 2022-02-10 WO claimed
US-20220039976-A1 ANTICOAGULANT COMPOUNDS AND METHODS AND DEVICES FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2022-02-10 US claimed
WO-2022026398-A1 COMBINATION THERAPY FOR CANCER THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-02-03 WO claimed
US-20100256131-A1 CARBONYL COMPOUNDS TSAKLAKIDIS CHRISTOS 2010-10-07 US claimed
US-20090221546-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE PFIZER INC 2009-09-03 US claimed
US-7407974-B2 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade PFIZER INC. (US) 2008-08-05 US claimed
US-20080003214-A1 Medicaments Comprising Carbonyl Compounds, And The Use Thereof MERCK PATENT GMBH (DE) 2008-01-03 US claimed
US-20060183739-A1 Carbonyl compounds MERCK PATENT GMBH (DE) 2006-08-17 US claimed
US-7030141-B2 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade WARNER-LAMBERT COMPANY LLC 2006-04-18 US claimed
EP-1465864-B1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER LAMBERT CO (US) 2006-03-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092380-A1 ANTIDOTES TO FACTOR XA INHIBITORS SERPINC1, F2, F8 F10 6/4885
US-20250186563-A1 UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME SERPINC1, F8, F9 F10 6/4885
US-20100256131-A1 CARBONYL COMPOUNDS F2, F11, PDHX F10 5/4885
US-20090221546-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE F11, F2, TFPI F10 10/4885
US-20080003214-A1 Medicaments Comprising Carbonyl Compounds, And The Use Thereof F2, PDHX, SDHB F10 22/4885
US-20060183739-A1 Carbonyl compounds F2, F11, PDHX F10 5/4885
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT SGMS1, SGMS2, MEN1 F10 1095/4885
US-12605371-B2 Combination therapy for cancer BRAF, TFPI, HGFAC F10 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.