Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847085 | 1.00 | ADORA2A (0.48) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL13843324 | 1.00 | ADORA2A (0.48) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL264091 | 1.00 | ADORA2A (0.48) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL264092 | 1.00 | ADORA2A (0.48) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| Hydrochloric Acid SCHEMBL3305326 | 0.99 | ADORA2A (0.47) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL14406302 | 0.87 | ADORA2A (0.39) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL13847172 | 0.87 | ADORA2A (0.35) | ADORA2AHIF1AADORA3 | |
| SCHEMBL264664 | 0.86 | ADORA2A (0.42) | ADORA2AHIF1API4KAPI4K2BPI4K2A | |
| SCHEMBL14064162 | 0.85 | ADORA2A (0.39) | ADORA2AADAADORA3ADORA2BADORA1 | |
| SCHEMBL264655 | 0.85 | ADORA3 (0.40) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893625-A2 | METHODS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES | Biocryst Pharmaceuticals, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2007002191-A2 | METHODS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | claimed |