Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 16/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964360 | 0.95 | MAPK7 (0.44) | MAPK7 | |
| SCHEMBL5078838 | 0.89 | MAPK7 (0.45) | MAPK7CHEK1 | |
| SCHEMBL4965011 | 0.84 | MAPK7 (0.52) | MAPK7 | |
| SCHEMBL4964717 | 0.84 | CHEK1 (0.48) | MAPK7CHEK1 | |
| SCHEMBL4963499 | 0.83 | MAPK7 (0.52) | MAPK7 | |
| SCHEMBL4964123 | 0.82 | MAP2K1 (0.39) | — | |
| SCHEMBL4963785 | 0.82 | MAPK7 (0.55) | MAPK7 | |
| SCHEMBL4963308 | 0.81 | MAPK7 (0.46) | MAPK7 | |
| SCHEMBL5075226 | 0.81 | AURKA (0.52) | MAPK7 | |
| SCHEMBL4962785 | 0.80 | MAPK7 (0.47) | MAPK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893598-A1 | ALKYLQUINOLINE AND ALKYLQUINAZOLINE KINASE MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006135721-A1 | ALKYLQUINOLINE AND ALKYLQUINAZOLINE KINASE MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-21 | — | — | WO | disclosed |