Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496300 | 1.00 | SLC18A3 (0.52) | SLC18A3ALDH1A1POLBSIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL496576 | 0.99 | SLC18A3 (0.51) | SLC18A3ALDH1A1POLBSIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL496575 | 0.99 | SLC18A3 (0.51) | SLC18A3ALDH1A1POLBSIGMAR1KMT2A | |
| SCHEMBL496223 | 0.93 | SLC18A3 (0.60) | SLC18A3SIGMAR1KMT2AMEN1TP53 | |
| SCHEMBL496506 | 0.92 | DRD2 (0.49) | SLC18A3ALDH1A1POLBCSNK1E | |
| SCHEMBL496505 | 0.92 | DRD2 (0.49) | SLC18A3ALDH1A1POLBCSNK1E | |
| Hydrochloric Acid SCHEMBL496080 | 0.92 | SLC18A3 (0.58) | SLC18A3SIGMAR1KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL496941 | 0.91 | DRD2 (0.48) | SLC18A3ALDH1A1POLBCSNK1E | |
| Hydrochloric Acid SCHEMBL496940 | 0.91 | DRD2 (0.48) | SLC18A3ALDH1A1POLBCSNK1E | |
| SCHEMBL12635754 | 0.80 | HDAC8 (0.43) | SLC18A3CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910317-B1 | 1-AMINO LINKED COMPOUNDS | LILLY CO ELI (US) | 2013-07-03 | — | — | EP | disclosed |
| US-8106090-B2 | Antidiabetic agents; prevent of non-insulin dependent diabetes | ELI LILLY AND COMPANY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20080207735-A1 | 1-Amino Linked Compounds | ELI LILLY AND COMPANY | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207735-A1 | 1-Amino Linked Compounds | DPP4, DPP3, DPP9 | SLC18A3 1288/4885ALDH1A1 1241/4885POLB 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.