Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963326 | 1.00 | TRPM8 (0.64) | TRPM8SNCABCHEACHEMEN1 | |
| SCHEMBL10270952 | 0.78 | TRPM8 (1.00) | TRPM8SNCABCHEACHEMEN1 | |
| SCHEMBL10270953 | 0.75 | TRPM8 (1.00) | TRPM8SNCAMEN1KMT2AGAA | |
| SCHEMBL14588686 | 0.74 | TRPM8 (0.64) | TRPM8SNCABCHEACHEMEN1 | |
| SCHEMBL8614182 | 0.73 | MAOB (0.69) | TRPM8BCHEMEN1KMT2ALMNA | |
| SCHEMBL8808072 | 0.72 | TRPM8 (0.58) | TRPM8SNCABCHEACHEMEN1 | |
| SCHEMBL30532218 | 0.72 | TRPM8 (1.00) | TRPM8SNCABCHEMEN1KMT2A | |
| SCHEMBL10270950 | 0.72 | TRPM8 (1.00) | TRPM8SNCABCHEMEN1KMT2A | |
| SCHEMBL28886282 | 0.71 | TRPM8 (0.66) | TRPM8LMNAGSK3BBACE1 | |
| SCHEMBL18536887 | 0.71 | TRPM8 (0.76) | TRPM8SNCABCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594880-B1 | PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION | OREAL (FR) | 2008-03-19 | — | — | EP | claimed |
| EP-1594880-A1 | PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION | L'OREAL (FR) | 2005-11-16 | — | — | EP | claimed |
| WO-2004067539-A1 | PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION | L'OREAL (FR) | 2004-08-12 | — | — | WO | claimed |