Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610256 | 1.00 | EPHX2 (0.66) | EPHX2KMT2AHSD11B1TDP1LMNA | |
| SCHEMBL610255 | 1.00 | EPHX2 (0.66) | EPHX2KMT2AHSD11B1TDP1LMNA | |
| SCHEMBL613063 | 0.91 | EPHX2 (0.79) | EPHX2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL613427 | 0.91 | EPHX2 (0.79) | EPHX2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL609675 | 0.91 | EPHX2 (0.79) | EPHX2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL610855 | 0.89 | EPHX2 (0.62) | EPHX2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL4963964 | 0.89 | EPHX2 (0.62) | EPHX2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL613383 | 0.88 | HSD11B1 (0.67) | EPHX2KMT2AHSD11B1TDP1ALDH1A1 | |
| SCHEMBL610977 | 0.88 | KMT2A (0.59) | EPHX2KMT2AHSD11B1TDP1LMNA | |
| SCHEMBL610357 | 0.88 | HSD11B1 (0.67) | EPHX2KMT2AHSD11B1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |