Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963947 | 1.00 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL5989738 | 0.94 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL4964726 | 0.94 | EGFR (0.84) | EGFRERBB2 | |
| Hki-357 SCHEMBL2203413 | 0.92 | EGFR (1.00) | EGFRERBB2 | |
| Hki-357 SCHEMBL29478857 | 0.92 | EGFR (1.00) | EGFRERBB2 | |
| Hki-357 SCHEMBL2203420 | 0.92 | EGFR (1.00) | EGFRERBB2 | |
| Hki-357 SCHEMBL29351364 | 0.92 | EGFR (1.00) | EGFRERBB2 | |
| Hki-357 SCHEMBL29351355 | 0.92 | EGFR (1.00) | EGFRERBB2 | |
| Hki-357 SCHEMBL2134691 | 0.91 | EGFR (0.93) | EGFRERBB2 | |
| SCHEMBL15320764 | 0.91 | EGFR (0.81) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883630-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | Wyeth (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20060270670-A1 | Methods of synthesizing 6-alkylaminoquinoline derivatives | WYETH | 2006-11-30 | — | — | US | disclosed |
| WO-2006127203-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270670-A1 | Methods of synthesizing 6-alkylaminoquinoline derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RECQL, NQO2 | EGFR 591/4885ERBB2 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.