Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.84 |
| ▸ | ERBB2 | P04626 | 19/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989738 | 1.00 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL4963941 | 0.94 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL4963947 | 0.94 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL5496959 | 0.93 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL5496956 | 0.93 | EGFR (0.86) | EGFRERBB2 | |
| SCHEMBL5499786 | 0.93 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL5499792 | 0.93 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL22847992 | 0.92 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL4962504 | 0.91 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL4962501 | 0.91 | EGFR (0.84) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883630-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | Wyeth (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006127203-A2 | METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |