⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14222839 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL10151378 | 0.78 | — | — | |
| SCHEMBL4722735 | 0.78 | — | — | |
| SCHEMBL8804004 | 0.78 | ALDH1A1 (0.45) | — | |
| Methylene Chloride SCHEMBL29108692 | 0.78 | ALDH1A1 (0.45) | — | |
| SCHEMBL10544891 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL10544887 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL16046411 | 0.75 | TSHR (0.47) | — | |
| SCHEMBL9649935 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL9649932 | 0.74 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890932-A | First total synthesis process of indole alkaloid Luteoride A | 大理大学 | 2022-08-12 | — | — | CN | claimed |
| US-12116372-B1 | Process for preparing methyl 3-bromo-2-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propanoate | BOULANGER WILLIAM ALLEN (US) | 2024-10-15 | — | — | US | disclosed |
| CN-111065626-B | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-117777051-B | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117777051-A | Synthesis method of 2-bromo-5-chlorothiazole-4-carboxylate | 山西永津集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-20220184219-A1 | Method of Making Prodrug for Sustained and Controlled Release | UNIVERSITY OF CINCINNATI (US) | 2022-06-16 | — | — | US | disclosed |
| CN-111065626-A | Compounds for the treatment of huntington's chorea | PTC医疗公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-3186267-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-10-02 | — | — | EP | disclosed |
| EP-3260462-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-04-17 | — | — | EP | disclosed |
| EP-1181288-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| US-6211360-B1 | DRUG ABRUSE THERAPY; PLANT EXTRACTS | ALBANY MEDICAL COLLEGE | 2001-04-03 | — | — | US | disclosed |
| WO-2000073301-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2000-12-07 | — | — | WO | disclosed |
| EP-0859610-A1 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997005869-A1 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 1997-02-20 | — | — | WO | disclosed |
| EP-0064317-B1 | PYRROLO(2,3-D)CARBAZOLE DERIVATIVES, PREPARATION THEREOF AND THEIR THERAPEUTICAL USE | OMNICHEM Société anonyme (BE) | 1986-02-26 | — | — | EP | disclosed |
| US-4560690-A | ANTISECRETORY AGENTS, HISTAMINE H2-ANTAGONISTS | PFIZER INC. (US) | 1985-12-24 | — | — | US | disclosed |
| US-4428880-A | Azepino[4,5-d]indole derivatives and preparation thereof | S.A. OMNICHEM (BE) | 1984-01-31 | — | — | US | disclosed |
| US-4362739-A | Pyrrolo(2,3-d)carbazole derivatives, compositions and use | S.A. OMNICHEM (BE) | 1982-12-07 | — | — | US | disclosed |
| EP-0064317-A2 | Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use | OMNICHEM Société anonyme (BE) | 1982-11-10 | — | — | EP | disclosed |