Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181789 | 0.76 | SMPD1 (0.41) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL28256972 | 0.76 | SMPD1 (0.41) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL28424850 | 0.76 | SMPD1 (0.41) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL28057025 | 0.76 | SMPD1 (0.41) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL10944414 | 0.71 | MEN1 (0.40) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL10943438 | 0.71 | MEN1 (0.40) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL10341597 | 0.71 | FDPS (0.47) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL11315446 | 0.71 | FDPS (0.47) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL28006927 | 0.71 | FDPS (0.36) | FDPSSMPD1CES2MEN1MAPT | |
| SCHEMBL1257556 | 0.71 | SMPD1 (0.43) | FDPSSMPD1CES2GGPS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883634-A2 | PROCESS FOR PREPARING SIMVASTATIN AND INTERMEDIATES THEREOF | Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság (HU) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007100351-A2 | PROCESS FOR PREPARING SIMVASTATIN AND INTERMEDIATES THEREOF | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2007-09-07 | — | — | WO | disclosed |