⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011517 | 0.80 | — | — | |
| SCHEMBL6368247 | 0.75 | — | — | |
| SCHEMBL11333278 | 0.75 | — | — | |
| SCHEMBL14255020 | 0.70 | — | — | |
| SCHEMBL10999283 | 0.65 | — | — | |
| SCHEMBL11167768 | 0.65 | — | — | |
| SCHEMBL27291909 | 0.65 | — | — | |
| SCHEMBL16198631 | 0.63 | RAB9A (0.44) | — | |
| SCHEMBL75716 | 0.61 | — | — | |
| SCHEMBL2046828 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | claimed |
| CN-118063470-A | Condensed imidazole derivatives substituted with tertiary hydroxyl groups as PI 3K-gamma inhibitors | 因赛特公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-111542526-B | Condensed imidazole derivatives substituted with tertiary hydroxyl groups as PI 3K-gamma inhibitors | 因赛特公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111542526-A | Condensed imidazole derivatives substituted by tertiary hydroxyl group as PI 3K-gamma inhibitor | 因赛特公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-108697089-A | The method for preventing and kill off plant insect | 巴斯夫欧洲公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108699075-A | Spirocyclic derivatives | 巴斯夫欧洲公司 | 2018-10-23 | — | — | CN | disclosed |
| EP-1888529-A2 | 3-CYANOQUINOLINE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | Wyeth (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20060264460-A1 | 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
| WO-2006124692-A2 | 3-CYANOQUINOLINE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060189650-A1 | Novel piperidine derivatives as modulators of chemokine receptor ccr5 | ASTRAZENECA AB (SE) | 2006-08-24 | — | — | US | disclosed |