Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GRM6 | O15303 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713203 | 0.89 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL10714409 | 0.84 | GRM6 (0.68) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL10713913 | 0.83 | GRM6 (0.76) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL1382025 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL4099130 | 0.80 | GRM6 (0.74) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL20665498 | 0.78 | GRM6 (0.62) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL1929543 | 0.77 | GRM6 (0.70) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL4561915 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL4093308 | 0.73 | GRM6 (0.49) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL3452499 | 0.72 | CYP1A2 (0.55) | ALDH1A1MAPTGAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436279-B1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-08-13 | — | — | EP | claimed |
| EP-1436279-B1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-08-13 | — | — | EP | disclosed |