Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 1.00 |
| ▸ | CA2 | P00918 | 19/20 | 1.00 |
| ▸ | CA9 | Q16790 | 8/20 | 0.72 |
| ▸ | CA12 | O43570 | 5/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA3 | P07451 | 2/20 | 0.72 |
| ▸ | CA6 | P23280 | 2/20 | 0.72 |
| ▸ | CA5A | P35218 | 2/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967450 | 0.85 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| Benzolamide SCHEMBL3497931 | 0.84 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL283024 | 0.83 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL9796165 | 0.82 | CA1 (0.76) | CA1CA2CA9CA12CA14 | |
| SCHEMBL9795893 | 0.82 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL9796270 | 0.82 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL282565 | 0.81 | CA1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL328336 | 0.78 | AKT1 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL11893060 | 0.78 | CA1 (0.81) | CA1CA2CA9CA12CA14 | |
| SCHEMBL14178520 | 0.76 | CA2 (0.75) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071421-A1 | NITRATE ESTERS OF CARBONIC ANHYDRASE INHIBITORS | NICOX S.A. (FR) | 2008-06-19 | — | — | WO | disclosed |