Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2370581 | 0.88 | — | — | |
| SCHEMBL21822839 | 0.86 | ITGB1 (0.33) | EPHX1ITGB1ITGA4 | |
| SCHEMBL1621823 | 0.76 | ITGB1 (0.43) | ITGB1ITGA4HSD11B1CA12CA1 | |
| SCHEMBL30633074 | 0.74 | ITGB1 (0.45) | ITGB1ITGA4HSD11B1CA12CA1 | |
| SCHEMBL4965234 | 0.74 | ALDH1A1 (0.51) | EPHX1ITGB1ITGA4HSD11B1CA12 | |
| SCHEMBL3682179 | 0.74 | HPGD (0.47) | HSD11B1 | |
| SCHEMBL4970937 | 0.73 | ITGB1 (0.34) | ITGB1ITGA4HSD11B1 | |
| SCHEMBL21798273 | 0.69 | KDM4E (0.36) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1620736 | 0.67 | ITGB1 (0.38) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7548688 | 0.67 | CA1 (0.37) | ITGB1ITGA4CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773780-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1773780-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006012227-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |