Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610063 | 0.95 | LTA4H (0.57) | LTA4HSLC6A2HRH2HTR2AHTR2B | |
| SCHEMBL7335832 | 0.94 | LTA4H (0.74) | LTA4HPOLB | |
| Hydrochloric Acid SCHEMBL7334091 | 0.93 | LTA4H (0.72) | LTA4HPOLBKMT2A | |
| SCHEMBL6611442 | 0.92 | LTA4H (0.62) | LTA4HPOLBKMT2A | |
| SCHEMBL13809106 | 0.89 | LTA4H (0.76) | LTA4HPOLB | |
| SCHEMBL7326422 | 0.89 | LTA4H (0.76) | LTA4HPOLB | |
| SCHEMBL7327575 | 0.89 | LTA4H (0.60) | LTA4HPOLBKMT2AHTR2B | |
| SCHEMBL14578215 | 0.88 | CHRNB4 (0.52) | LTA4HPOLB | |
| Hydrochloric Acid SCHEMBL4319150 | 0.87 | LTA4H (0.74) | LTA4HPOLB | |
| Hydrochloric Acid SCHEMBL7323937 | 0.87 | LTA4H (0.74) | LTA4HPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891051-A2 | SOLID FORMS OF 1-( 5-(IH-I , 2 , 4 -TRIAZOL- 5 -YL)(1H-INDAZOL-3-YL))-3-(2-PIPERIDYLETHOXY)BENZENE | CELGENE CORPORATION (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006130297-A2 | SOLID FORMS OF 1-( 5-(IH-I , 2 , 4 -TRIAZOL- 5 -YL)(1H-INDAZOL-3-YL))-3-(2-PIPERIDYLETHOXY)BENZENE | CELGENE CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| EP-1435955-A2 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SmithKline Beecham P.L.C. (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2002089800-A2 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-11-14 | — | — | WO | disclosed |
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0004288-A2 | Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation | MERCK PATENT GmbH (DE) | 1979-10-03 | — | — | EP | disclosed |