Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958219 | 0.79 | MAPT (0.41) | P2RX7MAPTTHRBKMT2ACTSA | |
| SCHEMBL4310574 | 0.75 | P2RX7 (0.52) | P2RX7TRPA1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL4962394 | 0.73 | CYP2D6 (0.38) | MAPTTHRBKMT2ACTSAALDH1A1 | |
| SCHEMBL4959671 | 0.71 | CYP1A2 (0.37) | MAPTTHRBCTSAALDH1A1AVPR2 | |
| SCHEMBL25345950 | 0.70 | POLB (0.41) | MAPTKMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4960190 | 0.70 | POLB (0.41) | MAPTKMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4957454 | 0.69 | SMN1; SMN2 (0.41) | MAPTTHRBKMT2AALDH1A1 | |
| SCHEMBL4311872 | 0.67 | P2RX7 (0.49) | P2RX7TRPA1SIGMAR1KMT2ACTSA | |
| SCHEMBL4958417 | 0.67 | MAPT (0.43) | MAPTTHRBKMT2ACTSAALDH1A1 | |
| SCHEMBL3447381 | 0.66 | CYP1A2 (0.46) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |