Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430997 | 0.94 | KMT2A (0.45) | KMT2AMEN1ALDH1A1THRBPKM | |
| SCHEMBL2426648 | 0.91 | MEN1 (0.44) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2425941 | 0.90 | KMT2A (0.48) | KMT2AMEN1ALDH1A1THRBPKM | |
| SCHEMBL2419999 | 0.88 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4ETHRB | |
| SCHEMBL2425542 | 0.88 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4ETHRB | |
| SCHEMBL2425308 | 0.85 | MEN1 (0.45) | KMT2AMEN1ALDH1A1KDM4ETHRB | |
| SCHEMBL2428956 | 0.85 | KMT2A (0.53) | KMT2AMEN1ALDH1A1THRBPKM | |
| SCHEMBL2423977 | 0.84 | KMT2A (0.48) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7448704 | 0.83 | MAPK9 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2420467 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |