Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2427138 | 0.96 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2AUBE2M | |
| SCHEMBL5002568 | 0.92 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2AUBE2M | |
| SCHEMBL7430997 | 0.88 | KMT2A (0.45) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2420588 | 0.87 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2426797 | 0.86 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2425308 | 0.86 | MEN1 (0.45) | MAPK9MAPK10MEN1KMT2AUBE2M | |
| SCHEMBL2424312 | 0.85 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AUBE2M | |
| SCHEMBL2422037 | 0.84 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL1518918 | 0.84 | MAPK9 (0.62) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL4189441 | 0.84 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |