Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961878 | 0.86 | HTT (0.50) | CNR2MAPTHTTMAPKAPK2LMNA | |
| SCHEMBL1336955 | 0.85 | BCL2A1 (0.49) | CNR2CNR1HTTMAPKAPK2SMN1; SMN2 | |
| SCHEMBL6732007 | 0.82 | HTT (0.49) | CNR2CNR1HTTLMNASMN1; SMN2 | |
| SCHEMBL23050841 | 0.79 | USP2 (0.49) | CNR2CNR1NR1H4LMNASMN1; SMN2 | |
| SCHEMBL6730973 | 0.78 | MAPT (0.51) | CNR2MAPTPDK1 | |
| SCHEMBL6727502 | 0.77 | LMNA (0.53) | CNR2MAPTCNR1HTTNR1H4 | |
| SCHEMBL15064523 | 0.75 | CNR2 (1.00) | CNR2CNR1NR1H4LMNASMN1; SMN2 | |
| SCHEMBL4966810 | 0.74 | HTT (0.49) | CNR2MAPTHTT | |
| Formic Acid SCHEMBL5034278 | 0.74 | CYP19A1 (0.43) | CNR2CNR1HTTNR1H4LMNA | |
| SCHEMBL3057341 | 0.73 | TSHR (0.59) | HTTNR1H4SMN1; SMN2PKMPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773780-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1773780-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006012227-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1773780-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1773780-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012227-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |